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Down syndrome is a set of cognitive and physical symptoms that result from having an extra chromosome 21 or an extra piece of that chromosome Health care providers can check for down syndrome during pregnancy or after a child is born. It is the most common chromosomal cause of mild to moderate intellectual disabilities

Understanding down syndrome and other intellectual and developmental disabilities is part of the reason nichd was established Down syndrome is the most frequent chromosomal cause of mild to moderate intellectual disability. Today, the institute continues to lead research on the causes, progression, treatment, and management of down syndrome, as well as on conditions and diseases that are associated with the syndrome.

The symptoms of down syndrome vary from person to person, and people with down syndrome may have different problems at different times of their lives.

People with down syndrome are at a greater risk for a number of health problems and conditions than are people who do not have down syndrome As the registry grows, families and researchers learn more about down syndrome and identify similarities and differences in the symptoms and treatment of people with down syndrome from around the world The information collected helps guide future research and treatment Down syndrome describes a set of cognitive and physical symptoms that result from an extra copy or part of a copy of chromosome 21.

Children with down syndrome are at an increased risk for some health problems, but not all will have serious health problems. Interferons are ‘cytokines’ that activate many different types of immune cells Interferon hyperactivity is a known risk factor for autoimmunity.

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